Enhancement of CDDP cytotoxicity by caffeine is characterized by apoptotic cell death.

@article{Takahashi1998EnhancementOC,
  title={Enhancement of CDDP cytotoxicity by caffeine is characterized by apoptotic cell death.},
  author={Maiko Takahashi and Yuji Yamamoto and Shinsuke Hatori and Manabu Shiozawa and Minako Suzuki and Yasushi Rino and Takayuki Amano and Toshio Imada},
  journal={Oncology reports},
  year={1998},
  volume={5 1},
  pages={53-6}
}
Through the use of STKM-1 human stomach cancer cells, we investigated the enhancement of the anti-tumor effect and the apoptosis induction of the CDDP and caffeine combination. Even when the concentration of CDDP was low, CDDP significantly decreased the proliferation of STKM-1 human stomach cancer cells, thus confirming the synergistic effect of the CDDP… CONTINUE READING