Enhancement in Sustained Release of Antimicrobial Peptide from Dual-Diameter-Structured TiO2 Nanotubes for Long-Lasting Antibacterial Activity and Cytocompatibility.

Abstract

Novel films on Ti-based orthopedic implants for localized antimicrobial delivery, which comprises dual-diameter TiO2 nanotubes with the inner layers of compact and fluorine-free oxide tightly bonding to Ti, were formed by voltage-increased anodization with F- sedimentation procedure. The nanotubes were closely aligned and structured with upper 35 and 70 nm… (More)
DOI: 10.1021/acsami.7b00322

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