Enhanced virulence of Escherichia coli bearing a site-targeted mutation in the major structural subunit of type 1 fimbriae.

@article{May1993EnhancedVO,
  title={Enhanced virulence of Escherichia coli bearing a site-targeted mutation in the major structural subunit of type 1 fimbriae.},
  author={Addison K. May and Craig A. Bloch and Robert G. Sawyer and Michael D Spengler and Timothy L. Pruett},
  journal={Infection and immunity},
  year={1993},
  volume={61 5},
  pages={1667-73}
}
Type 1 fimbriae promote enterobacterial adherence to a variety of mammalian cells and are thought to play an important role in the establishment of various extraintestinal infections. Whether or not this adhesin has a role in the pathogenesis of peritoneal Escherichia coli infections, such as those initiated by bowel leakage during intraabdominal surgery… CONTINUE READING