Enhanced transcytosis of R5-tropic human immunodeficiency virus across tight monolayer of polarized human endometrial cells under pro-inflammatory conditions.

@article{Carreno2002EnhancedTO,
  title={Enhanced transcytosis of R5-tropic human immunodeficiency virus across tight monolayer of polarized human endometrial cells under pro-inflammatory conditions.},
  author={M P Carreno and Corrine Krieff and Th{\'e}ano Irinopoulou and Michel Daniel Kazatchkine and Laurent B{\'e}lec},
  journal={Cytokine},
  year={2002},
  volume={20 6},
  pages={289-94}
}
Most cases of human immunodeficiency virus (HIV) infection worldwide occur following sexual contact, implying that the virus may breach the protective epithelial barrier lining the genital tract. HIV infection is known to preferentially occur when the genital epithelial integrity is altered, particularly when epithelial micro-ulcerations occur during heterosexual intercourse or ulcerations appear, due to sexually transmitted infections or else in the context of ectopy of the endocervical mucosa… CONTINUE READING

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