Enhanced thrombin generation and reduced intact protein S in processed solvent detergent plasma.

BACKGROUND Standardized solvent/detergent (S/D)-treated plasma has been developed as an improved alternative to fresh frozen-plasma (FFP) in the management of severe bleeds. This study aimed at exploring compositional modifications that may influence the general applicability of S/D-treated plasma. MATERIALS AND METHODS S/D-treated plasma and FFP were… CONTINUE READING