Enhanced susceptibility to cytotoxic T lymphocytes of target cells isolated from virus-infected or interferon-treated mice.

@article{Bukowski1986EnhancedST,
  title={Enhanced susceptibility to cytotoxic T lymphocytes of target cells isolated from virus-infected or interferon-treated mice.},
  author={Jack F. Bukowski and Raymond M. Welsh},
  journal={Journal of virology},
  year={1986},
  volume={59 3},
  pages={735-9}
}
Bone marrow cells and thymocytes isolated from virus-infected or interferon (IFN)-treated mice had marked increases in sensitivity to lysis by allospecific cytotoxic T lymphocytes (CTL) and in expression of class I histocompatibility antigens. Cultured fibroblasts treated with IFN in vitro yielded similar findings in addition to having increased sensitivity to lysis by virus-specific CTL. This indicates that virus-induced IFN may condition target cells in vivo for surveillance by CTL. 

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