Enhanced subendocardial perfusion distal to a flow-limiting coronary artery stenosis in dogs: comparative effects of nicorandil, a potential new antianginal agent, and nitroglycerin.

Abstract

The purpose of this study was to compare the effects of nicorandil [SG-75; 2-nicotinamidoethyl nitrate (ester)] and nitroglycerin on the distribution of blood flow between subendocardium and subepicardium [endocardial/epicardial blood flow ration (endo/epi)] distal to a proximal flow-limiting coronary artery stenosis in anesthetized dogs. Myocardial blood… (More)

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Cite this paper

@article{Gross1985EnhancedSP, title={Enhanced subendocardial perfusion distal to a flow-limiting coronary artery stenosis in dogs: comparative effects of nicorandil, a potential new antianginal agent, and nitroglycerin.}, author={Garrett John Gross and David C. Warltier and Harold F. Hardman and Kathleen A Lamping}, journal={Journal of cardiovascular pharmacology}, year={1985}, volume={7 5}, pages={977-82} }