Enhanced stress analgesia to a cognitively demanding task in patients with posttraumatic stress disorder.

@article{Diener2012EnhancedSA,
  title={Enhanced stress analgesia to a cognitively demanding task in patients with posttraumatic stress disorder.},
  author={Slawomira J. Diener and Mich{\`e}le Wessa and St{\'e}phanie De Ridder and Simone Lang and Martin Diers and Regina Steil and Herta Flor},
  journal={Journal of affective disorders},
  year={2012},
  volume={136 3},
  pages={
          1247-51
        }
}
BACKGROUND Uncontrollable stress is frequently accompanied by a primarily opioid-mediated stress analgesia. In posttraumatic stress disorder (PTSD) exaggerated stress-induced analgesia to trauma reminders was proposed. The present study investigated whether enhanced analgesia occurs in response to a trauma-unrelated cognitive stressor in PTSD. METHODS Functional magnetic resonance imaging data were obtained from fourteen outpatients with PTSD and 14 trauma-exposed subjects without PTSD (NPTSD… CONTINUE READING
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