Enhanced stimulant and metabolic effects of combined ephedrine and caffeine.

@article{Haller2004EnhancedSA,
  title={Enhanced stimulant and metabolic effects of combined ephedrine and caffeine.},
  author={Christine Haller and Peyton Jacob and Neal L. Benowitz},
  journal={Clinical pharmacology and therapeutics},
  year={2004},
  volume={75 4},
  pages={
          259-73
        }
}
  • Christine Haller, Peyton Jacob, Neal L. Benowitz
  • Published 2004
  • Medicine
  • Clinical pharmacology and therapeutics
  • OBJECTIVE Herbal weight loss and athletic performance-enhancing supplements that contain ephedrine and caffeine have been associated with serious adverse health events. We sought to determine whether ephedrine and caffeine have clinically significant pharmacologic interactions that explain these toxicities. METHODS Sixteen healthy adults ingested 25 mg ephedrine, 200 mg caffeine, or both drugs in a randomized, double-blind, placebo-controlled crossover study. Plasma and urine samples were… CONTINUE READING

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