Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats.

@article{Li1989EnhancedSR,
  title={Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats.},
  author={Ping Li and Edwin K Jackson},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1989},
  volume={251 3},
  pages={
          909-21
        }
}
Rapid-pressor and slow-pressor responses to angiotensin (ANG) II and norepinephrine (NE) in spontaneously hypertensive rats (SHR) and Wistar Kyoto control rats (WKY) were examined. All animals were treated from 4 wk of age with captopril (100 mg/kg/day in drinking water) to prevent development of hypertension so that changes in responsiveness could not be attributed to disparate base-line blood pressures or to hypertension-induced injury of the cardiovascular system. In 11-wk, conscious… CONTINUE READING

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