Enhanced sensitivity to stimulation of sodium transport and cyclic AMP by antidiuretic hormone after Ca2+ depletion of isolated frog skin epithelium


The role of Ca2+ in the stimulation by antidiuretic hormone (ADH) of active sodium transport across the isolated epithelium of frog skin was investigated. This has been done by bathing the blood side with Ca2+-free solution containing 0.1mm EGTA. This Ca2+ depletion halved the resistance but had no significant effect on the short-circuit current (SCC). The… (More)
DOI: 10.1007/BF01872273


6 Figures and Tables