Enhanced response of subfornical organ neurons projecting to the hypothalamic paraventricular nucleus to angiotensin II in spontaneously hypertensive rats.

@article{Miyakubo2002EnhancedRO,
  title={Enhanced response of subfornical organ neurons projecting to the hypothalamic paraventricular nucleus to angiotensin II in spontaneously hypertensive rats.},
  author={Hiroko Miyakubo and Yasushi Hayashi and Junichi Tanaka},
  journal={Autonomic neuroscience : basic & clinical},
  year={2002},
  volume={95 1-2},
  pages={131-6}
}
Thirty subfornical organ (SFO) neurons in normotensive Wistar-Kyoto (WKY) rats and 32 SFO neurons in spontaneously hypertensive rats (SHR) were antidromically activated by electrical stimulation of the hypothalamic paraventricular nucleus (PVN) under urethane anesthesia. The spontaneous firing rate was significantly higher in SHR than in WKY rats. No significant differences in the latency, conduction velocity, and threshold of antidromic response were observed between WKY and SHR. All the… CONTINUE READING