Enhanced precision with dual-energy x-ray absorptiometry

  title={Enhanced precision with dual-energy x-ray absorptiometry},
  author={Richard B Mazess and Charles H. Chesnut and Michael R. McClung and Harry K. Genant},
  journal={Calcified Tissue International},
SummaryRepeat spine and femur measurements (5 per case) were done on 19 subjects with the DPX-L densitometer operating at 3 mA giving a radiation flux fourfold higher than the earlier DPX model. The precision for spine bone mineral density (BMD) was about 0.55% (L2–L4) and 0.48% (L1–L4) for 2-minute scans (2.4 mrem). The precision was only slightly lower (0.4–0.5%) for 4-minute scans (5 mrem) in a subset of 11 subjects. There was a slight precision advantage for the larger L1–L4 area compared… 

Precision of dual x-ray absorptiometry and peripheral computed tomography using mobile densitometry units

In conclusion, mobile densitometry may become a useful tool not only for epidemiologic surveys and clinical trials but also for routine evaluation in less densely populated areas.

Comparison of ultrasound and dual energy X-ray absorptiometry measurements in the calcaneus.

BMD of the calcaneus, when closely matched to the site of ultrasound measurement shows significant correlation with ultrasound measurements, but this result still does not explain all of the variance in the ultrasound results.

Factors influencing short-term precision of dual X-ray bone absorptiometry (DXA) of spine and femur

Therefore, particularly in the femur and in the decubitus lateral modes, the use of BMD is advantageous compared with BMC, and a higher dependence of BMC changes on AREA changes resulted in a larger difference between BMC and BMD precision.

Which vertebrae should be assessed using lateral dual-energy X-ray absorptiometry of the lumbar spine

L4 and combinations of vertebrae including L4 showed the best discriminatory capabilities with respect to vertebral fractures in receiver operating characteristic (ROC) analyses,t-tests andZ-scores, with smaller variability of the results when multiple vertebral levels were used.

Determination of baseline bone mineral density using dual energy X-ray absorptiometry in Suffolk-Dorset hybrid ewes

Bone density testing.

  • M. Colyar
  • Medicine, Physics
    Advance for nurse practitioners
  • 2004
Bone density testing is a medical procedure used to determine bone density or strength and the majority are quick and pain-free.

Densitometer type and impact on risk assessment for osteoporosis.

This study cautions against the use of non established densitometers that leads to underdiagnosis of patients and, subsequently, to inappropriate treatment strategies.

Age changes of spine density in posterior-anterior and lateral projections in normal women

The ability to detect age changes in an individual subject can be increased only if the precision error for lateral spine BMD is not increased to a greater extent than the sensitivity; the lateral spine still showed the highest sensitivity to aging.

Prescreening for osteoporosis with forearm bone densitometry in health examination population

Peripheral DXA appears to be a reliable tool for prescreening for osteoporosis screening using manufacturer-supplied density-gradient phantoms and volunteers to investigate its accuracy and precision.

Assessment of bone mineral density with dual energy X-ray absorptiometry in pre- and post-menopausal women

It is found that the FN had significantly lower T-score than LS for both preand post-menopausal women, in spite of the reported lower BMD T-scores for the LS compared with the FN for women.



Quantitative digital radiography versus dual photon absorptiometry of the lumbar spine.

Quantitative digital radiography's image resolution was superior to that of DPA, enabling it to measure more bones, and the elimination of 153Gd source changes and Nuclear Regulatory Commission licensing requirements indicate that quantitativedigital radiography is the superior method for spinal BMD measurements.

Longitudinal precision of dual‐energy X‐ray absorptiometry in a multicenter study

  • E. OrwollShelia K. Oviatt
  • Medicine
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 1991
DEXA demonstrates good in vitro and in vivo longitudinal precision, providing the basis for expanded clinical and research usefulness, Nevertheless, stringent quality assurance measures are required to detect and respond to system malfunctions.

Intersite comparison of the Hologic QDR-1000 dual energy X-ray bone densitometer.

Differences in calibration between systems were generally less than 1%; variations in results resulting from Differences in analytical technique were more significant than those resulting from differences in calibration.

In vivo and in vitro precision for bone density measured by dual-energy X-ray absorption

An investigation was made into some of the major sources of error influencing the bone mineral density measurements of the lumbar vertebrae, the femoral neck and the greater trochanter, suggesting that most of the variation in the femur density results can be attributed to the analysis procedure.

Automated comparison of dual‐photon absorptiometric studies of the lumbar spine

An automated image comparison procedure was developed to optimize the precision of bone mineral density measurements by dual‐photon absorptiometry, and improved precision with respect to manual analysis was yielded.

Relationship between patient exposure and measurement precision in dual-photon absorptiometry of the spine.

Investigation of the relationship between patient exposure and measurement precision in dual-photon absorptiometry indicates that currently available systems are capable of operating at or near the limits of statistical precision per unit of patient exposure.

Bone densitometry of the axial skeleton.

  • R. Mazess
  • Medicine, Physics
    The Orthopedic clinics of North America
  • 1990
The QCT method and the DPA/DEXA method are discussed separately, including their regions of interest, calibration, radiation dose, diagnostic sensitivity, precision, and the monitoring and accuracy of changes.

Dual-energy radiographic absorptiometry for bone densitometry: current status and perspective.

Speed and comparability of 3 dual-energy X-ray absorptiometer (DXA) models

  • 1990