Enhanced polarization of embryonic hippocampal neurons on micron scale electrospun fibers.

@article{Lee2010EnhancedPO,
  title={Enhanced polarization of embryonic hippocampal neurons on micron scale electrospun fibers.},
  author={Jae Young Lee and Chris A Bashur and Natalia Cald{\'e}s Gomez and Aaron S. Goldstein and Christine E. Schmidt},
  journal={Journal of biomedical materials research. Part A},
  year={2010},
  volume={92 4},
  pages={1398-406}
}
Electrospun fibers have been fabricated for wide use as artificial tissue engineering scaffolds. In particular, fibers smaller than a cell body have been extensively employed to mimic natural extracellular matrix (ECM) and to explore specific responses by various cell types. We investigated the effects of various poly(lactic acid-co-glycolic acid) (PLGA) fiber features on embryonic hippocampal neurons in the early developmental stages in terms of initial axon formation (i.e., polarization) and… CONTINUE READING
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