Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene

@article{Lim2004EnhancedPP,
  title={Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene},
  author={M. Lim and Z. Wang and D. E. Olaz{\'a}bal and X. Ren and E. Terwilliger and L. Young},
  journal={Nature},
  year={2004},
  volume={429},
  pages={754-757}
}
  • M. Lim, Z. Wang, +3 authors L. Young
  • Published 2004
  • Biology, Medicine
  • Nature
  • The molecular mechanisms underlying the evolution of complex behaviour are poorly understood. The mammalian genus Microtus provides an excellent model for investigating the evolution of social behaviour. Prairie voles (Microtus ochrogaster) exhibit a monogamous social structure in nature, whereas closely related meadow voles (Microtus pennsylvanicus) are solitary and polygamous. In male prairie voles, both vasopressin and dopamine act in the ventral forebrain to regulate selective affiliation… CONTINUE READING
    527 Citations

    Figures and Topics from this paper

    Gene regulation as a modulator of social preference in voles.
    • 23
    Monogamy evolves through multiple mechanisms: evidence from V1aR in deer mice.
    • 88
    • Highly Influenced
    • PDF
    Mammalian monogamy is not controlled by a single gene.
    • 122
    • PDF
    Individual Differences in Social Behavior and Cortical Vasopressin Receptor: Genetics, Epigenetics, and Evolution
    • 4
    • PDF
    Polymorphism at the avpr1a locus in male prairie voles correlated with genetic but not social monogamy in field populations
    • 63
    Variation in vasopressin receptor (Avpr1a) expression creates diversity in behaviors related to monogamy in prairie voles
    • 68
    Distributions of oxytocin and vasopressin 1a receptors in the Taiwan vole and their role in social monogamy.
    • 9

    References

    SHOWING 1-10 OF 36 REFERENCES
    Functional microsatellite polymorphism associated with divergent social structure in vole species.
    • 122
    • PDF
    Extraordinary diversity in vasopressin (V1a) receptor distributions among wild prairie voles (Microtus ochrogaster): Patterns of variation and covariation
    • 104
    • PDF
    Patterns of brain vasopressin receptor distribution associated with social organization in microtine rodents
    • T. Insel, Z. Wang, C. Ferris
    • Biology, Medicine
    • The Journal of neuroscience : the official journal of the Society for Neuroscience
    • 1994
    • 391
    • PDF
    Species differences in V1a receptor gene expression in monogamous and nonmonogamous voles: behavioral consequences.
    • 223
    Monogamy in Mammals
    • D. Kleiman
    • Biology, Medicine
    • The Quarterly Review of Biology
    • 1977
    • 1,250