Enhanced oxidative stress and endothelial dysfunction in streptozotocin-diabetic rats exposed to fine particles.

@article{Lei2005EnhancedOS,
  title={Enhanced oxidative stress and endothelial dysfunction in streptozotocin-diabetic rats exposed to fine particles.},
  author={Yu-Chen Lei and Jing-Shiang Hwang and Chang-Chuan Chan and Chung-Te Lee and Tsun-Jen Cheng},
  journal={Environmental research},
  year={2005},
  volume={99 3},
  pages={335-43}
}
The association between ambient particulate matter (PM) and cardiovascular diseases has been demonstrated in epidemiological studies. Recent studies suggest that diabetic patients are at greater risk for PM-associated cardiovascular events. Although diabetes and PM exposure individually have been reported to be associated with increased oxidative stress, inflammation, and endothelial dysfunction, it is not clear whether PM may induce synergistic interaction effects on these parameters in… CONTINUE READING
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