Enhanced oxidant stress in synovial vessels of patients on hemodialysis.

  title={Enhanced oxidant stress in synovial vessels of patients on hemodialysis.},
  author={FanFan Hou and Guohua Wang and Zhi-bin Zhou and Xiao-yi Zhang},
  journal={Chinese medical journal},
  volume={113 10},
OBJECTIVE To test the hypothesis that the susceptibility of synovial vessels to redox uncoupling which could result in oxidative damage capable of promoting beta 2-microglobulin (beta 2 m) deposition. METHODS The expression of oxidative markers by microvascular endothelial cells in hemodialysis (HD) patients, non-uremic patients and normal subjects was determined using immunostaining and Northern blotting. RESULTS Synovial vascular endothelial cells of HD patients exhibited evidence of… CONTINUE READING

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