Enhanced oscillatory activity in the hippocampal-prefrontal network is related to short-term memory function after early-life seizures.

@article{Kleen2011EnhancedOA,
  title={Enhanced oscillatory activity in the hippocampal-prefrontal network is related to short-term memory function after early-life seizures.},
  author={Jonathan K. Kleen and Edie X Wu and Gregory L. Holmes and Rod C. Scott and Pierre-Pascal Lenck-Santini},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 43},
  pages={15397-406}
}
Neurological insults during development are associated with later impairments in learning and memory. Although remedial training can help restore cognitive function, the neural mechanisms of this recovery in memory systems are largely unknown. To examine this issue, we measured electrophysiological oscillatory activity in the hippocampus (both CA3 and CA1) and prefrontal cortex of adult rats that had experienced repeated seizures in the first weeks of life, while they were remedially trained on… CONTINUE READING

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The long-term effects of neonatal seizures

GL Holmes
Clin Perinatol 36:901–914, • 2009
View 4 Excerpts
Highly Influenced

Effects of ibotenate hippocampal and extrahippocampal destruction on delayed-match and -nonmatch-to-sample behavior in rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1999
View 4 Excerpts
Highly Influenced

Brain plasticity as a basis for recovery of function in humans

Neuropsychologia • 1990
View 4 Excerpts
Highly Influenced

Epidemiology of epilepsy in children.

Cleveland Clinic journal of medicine • 1989
View 6 Excerpts
Highly Influenced

Gamma oscillations dynamically couple hippocampal CA3 and CA1 regions during memory task performance.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 4 Excerpts
Highly Influenced

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