Enhanced myogenic response in the afferent arteriole of spontaneously hypertensive rats.


Spontaneously hypertensive rats (SHRs) have normal glomerular capillary pressure even though renal perfusion pressure is higher, suggesting that preglomerular vessels exhibit abnormally high resistance. This may be due to increased superoxide (O(2)(-)) production, which contributes to the vasoconstriction in hypertension. We tested the hypothesis that the… (More)
DOI: 10.1152/ajpheart.00537.2009

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