Enhanced metabolism of Leishmania donovani amastigotes at acid pH: an adaptation for intracellular growth.


Amastigotes (tissue forms) of Leishmania donovani isolated from infected hamster spleens carried out several physiological activities (respiration, catabolism of energy substrates, and incorporation of precursors into macromolecules) optimally at pH 4.0 to 5.5. All metabolic activities that were examined decreased sharply above the optimal pH. Promastigotes… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.