Enhanced lipolysis is not evident in adipocytes from exercise-trained SHR.

@article{Shepherd1986EnhancedLI,
  title={Enhanced lipolysis is not evident in adipocytes from exercise-trained SHR.},
  author={Raymond E. Shepherd and Mamadou Diawo Bah and Karl M. Nelson},
  journal={Journal of applied physiology},
  year={1986},
  volume={61 4},
  pages={1301-8}
}
Adipocytes from spontaneously hypertensive rats (SHR) are not as responsive to isoproterenol or dibutyryl adenosine 3',5'-cyclic monophosphate (cAMP) stimulation compared with Sprague-Dawley or Wistar-Kyoto rats. Lipolytic activity in adipocytes from trained normotensive rats was enhanced in response to 1 microM isoproterenol and 0.5 mM dibutyryl cAMP but not in adipocytes from trained SHR. Decreases in isoproterenol-stimulated (1 microM) cAMP accumulation were evident in adipocytes from… CONTINUE READING