Enhanced large intestinal potassium permeability in end‐stage renal disease

@article{Mathialahan2005EnhancedLI,
  title={Enhanced large intestinal potassium permeability in end‐stage renal disease},
  author={T. Mathialahan and K. Maclennan and L. Sandle and C. Verbeke and G. Sandle},
  journal={The Journal of Pathology},
  year={2005},
  volume={206}
}
The capacity of the colon for potassium (K+) secretion increases in end‐stage renal disease (ESRD), to the extent that it makes a substantial contribution to K+ homeostasis. This colonic K+ adaptive response may reflect enhanced active K+ secretion, and be associated with an increase in apical membrane K+ permeability. In this study, this hypothesis was tested in patients with normal renal function or ESRD, by evaluating the effect of barium ions (a K+ channel inhibitor) on rectal K+ secretion… Expand
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