Enhanced insecticidal activity of Chilo iridescent virus expressing an insect specific neurotoxin.

@article{Nalaciolu2016EnhancedIA,
  title={Enhanced insecticidal activity of Chilo iridescent virus expressing an insect specific neurotoxin.},
  author={Remziye Nalçacioğlu and Hacer Muratoğlu and Aydın Yesilyurt and Monique M. van Oers and Just M. Vlak and Zihni Demirbağ},
  journal={Journal of invertebrate pathology},
  year={2016},
  volume={138},
  pages={
          104-11
        }
}
Previously we have generated a recombinant Chilo iridescent virus (CIV) by inserting the green fluorescent protein gene (gfp) into the CIV 157L open reading frame (ORF) locus and showed that this recombinant (rCIV-Δ157L-gfp) was fully infectious both in cell culture as well as in insect larvae. This study opened up a new avenue for increasing the speed of kill of CIV and other iridoviruses by inserting virulence or toxin genes into the viral genome. In the current study we constructed a… CONTINUE READING
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