Enhanced immunogenicity of an oral inactivated cholera vaccine in infants in Bangladesh obtained by zinc supplementation and by temporary withholding breast-feeding.

@article{Ahmed2009EnhancedIO,
  title={Enhanced immunogenicity of an oral inactivated cholera vaccine in infants in Bangladesh obtained by zinc supplementation and by temporary withholding breast-feeding.},
  author={Tanvir Ahmed and A M Svennerholm and Abdullah Al Tarique and Gazi Nurun Nahar Sultana and Firdausi Qadri},
  journal={Vaccine},
  year={2009},
  volume={27 9},
  pages={1433-9}
}
The killed oral cholera vaccine Dukoral is recommended for adults and only children over 2 years of age, although cholera is seen frequently in younger children and there is an urgent need for a vaccine for them. Since decreased immunogenicity of oral vaccines in children in developing countries is a critical problem, we tested interventions to enhance responses to Dukoral. We evaluated the effect on the immune responses by temporarily withholding breast-feeding or by giving zinc… CONTINUE READING

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