Enhanced healing of rat calvarial defects with sulfated chitosan-coated calcium-deficient hydroxyapatite/bone morphogenetic protein 2 scaffolds.

@article{Zhao2012EnhancedHO,
  title={Enhanced healing of rat calvarial defects with sulfated chitosan-coated calcium-deficient hydroxyapatite/bone morphogenetic protein 2 scaffolds.},
  author={Jun Zhao and Gefengqiang Shen and Changsheng Liu and Shaoyi Wang and Wenjie Zhang and Xiaochen Zhang and Xiuli Zhang and Dongxia Ye and Jie Wei and Zhiyuan Zhang and Xinquan Jiang},
  journal={Tissue engineering. Part A},
  year={2012},
  volume={18 1-2},
  pages={
          185-97
        }
}
Calcium phosphate cements (CPCs), which are widely used in bone regeneration, possess good biocompatibility and osteoconductivity and have been demonstrated to be candidate carriers for bone growth factors. However, limited release of growth factors from CPCs and slow degradation of the materials are not desirable for certain clinical applications. Previous studies have shown that calcium-deficient hydroxyapatite (CDHA) from CPCs presents more rapid degradation rate than CPCs. In this study, a… CONTINUE READING
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