Enhanced gene expression of endothelial nitric oxide synthase in brown adipose tissue during cold exposure.

@article{KikuchiUtsumi2002EnhancedGE,
  title={Enhanced gene expression of endothelial nitric oxide synthase in brown adipose tissue during cold exposure.},
  author={Kazue Kikuchi-Utsumi and Bihu Gao and Hiroshi Ohinata and Masaaki Hashimoto and Noriyuki Yamamoto and Akihiro Kuroshima},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2002},
  volume={282 2},
  pages={
          R623-6
        }
}
It has been shown that norepinephrine (NE) can mediate vasodilatation by stimulating the production of nitric oxide (NO) in brown adipose tissue (BAT), resulting in an increase in BAT blood flow. We speculated that constitutive NO synthase (NOS) is involved in this NO production. However, it is not known whether constitutive NOS is expressed in BAT. To answer this question, we assessed the expression of two types of constitutive NOS, endothelial (eNOS) and neuronal NOS (nNOS), in BAT of rats… CONTINUE READING
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