Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis.

@article{Achkor2003EnhancedFD,
  title={Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis.},
  author={Hakima Achkor and Maykelis D{\'i}az and Maria Rosario Fern{\'a}ndez and Josep Antoni Biosca and Xavier Par{\'e}s and Mar{\'i}a del Carmen Mart{\'i}nez},
  journal={Plant physiology},
  year={2003},
  volume={132 4},
  pages={2248-55}
}
The ADH2 gene codes for the Arabidopsis glutathione-dependent formaldehyde dehydrogenase (FALDH), an enzyme involved in formaldehyde metabolism in eukaryotes. In the present work, we have investigated the potential role of FALDH in detoxification of exogenous formaldehyde. We have generated a yeast (Saccharomyces cerevisiae) mutant strain (sfa1Delta) by in vivo deletion of the SFA1 gene that codes for the endogenous FALDH. Overexpression of Arabidopsis FALDH in this mutant confers high… CONTINUE READING
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The utilization of carbon - 1 compounds by plants . I . The metabolism of methanol - C 14 and its role in amino acid biosynthesis

  • EA Cossins
  • Can J Biochem
  • 1964
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