Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain.

@article{Schnemeier2008EnhancedEO,
  title={Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain.},
  author={Bastian Sch{\"o}nemeier and Stefan Schulz and Volker Hoellt and Ralf Stumm},
  journal={Journal of neuroimmunology},
  year={2008},
  volume={198 1-2},
  pages={39-45}
}
Expression patterns of the second SDF-1 receptor RDC1/CXCR7 were examined after focal ischemia in rats using in situ hybridization. CXCR7 mRNA was identified in the ventricle walls as well as neuronal, astroglial, and vascular cells. After ischemia, intact cortical regions showed a rapid, 4 days-lasting increase in neuronal CXCR7 expression. In the ischemic tissue CXCR7 expression was scarce and associated with blood vessels. Between days 2 and 10 after ischemia-onset, SDF-1 expression… CONTINUE READING

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