Enhanced expression of rat hepatic CYP2B1/2B2 and 2E1 by pyridine: differential induction kinetics and molecular basis of expression.

Abstract

Expression of the cytochrome P450 (CYP) 2B subfamily in rat and rabbit hepatic tissues after pyridine (PY) treatment has been examined, and the molecular basis for enhanced 2B1/2B2 expression has been determined. P450 expression was monitored using metabolic activity, sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblot analyses, and the… (More)

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Cite this paper

@article{Kim1993EnhancedEO, title={Enhanced expression of rat hepatic CYP2B1/2B2 and 2E1 by pyridine: differential induction kinetics and molecular basis of expression.}, author={H. Kim and Doug Putt and S. Reddy and Paul F. Hollenberg and Rostislav Novak}, journal={The Journal of pharmacology and experimental therapeutics}, year={1993}, volume={267 2}, pages={927-36} }