Enhanced expression of neurotensin/neuromedin N mRNA and products of NT/NMN precursor processing in neonatal rats

@article{Muraki1993EnhancedEO,
  title={Enhanced expression of neurotensin/neuromedin N mRNA and products of NT/NMN precursor processing in neonatal rats},
  author={Koutarou Muraki and S. P. Mitra and P. Dobner and R. Carraway},
  journal={Peptides},
  year={1993},
  volume={14},
  pages={1095-1102}
}
  • Koutarou Muraki, S. P. Mitra, +1 author R. Carraway
  • Published 1993
  • Biology, Medicine
  • Peptides
  • Intestinal levels of immunoreactive neurotensin (iNT) and neuromedin N (iNMN), as well as mRNA for the NT/NMN precursor, were elevated during the suckling period in rats. While transient expression of NT/NMN was observed at 1-5 days of age in the proximal small intestine and colon, NT/NMN levels in the ileum increased to peak at 10-20 days of age and then decreased to adult levels. The levels of these peptides were not elevated in the central nervous system and pituitary over this time period… CONTINUE READING
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    References

    SHOWING 1-10 OF 34 REFERENCES
    Differential processing of neurotensin/neuromedin N precursor(s) in canine brain and intestine.
    • 50
    Presence of neurotensin and neuromedin-N within a common precursor from a human pancreatic neuroendocrine tumor.
    • 21
    Biosynthesis, Maturation, Release, and Degradation of Neurotensin and Neuromedin N
    • 67
    Age-dependent increase of neurotensin expression in the ileum.
    • 7
    Distribution of neurotensin/neuromedin N mRNA in rat forebrain: unexpected abundance in hippocampus and subiculum.
    • 114
    • PDF
    Purification of large neuromedin N (NMN) from canine intestine and its identification as NMN-125.
    • 19