Enhanced enteric excretion of urate in rats with chronic renal failure.

1. The potential contribution of enteric pathways to the extra-renal excretion of uric acid in chronic renal failure was evaluated by measuring [14C]-urate and 36Cl- transport in isolated, short-circuited segments of jejunum, ileum and distal colon from normal rats and rats with chronic renal failure (five-sixths nephrectomized) 6 weeks after surgery… CONTINUE READING