Enhanced endocrine response to novel environment stress and lack of corticosterone circadian rhythm in staggerer (Rora sg/sg) mutant mice.

Abstract

The staggerer (Rora sg/sg) mutation is a deletion in the retinoid-related orphan receptor (RORalpha) gene that prevents translation of the ligand-binding domain (LBD), leading to the loss of RORalpha activity. RORalpha is a transcription factor that belongs to the nuclear receptor superfamily. In the brain, RORalpha is expressed in specific areas, including… (More)

Topics

Cite this paper

@article{Frdric2006EnhancedER, title={Enhanced endocrine response to novel environment stress and lack of corticosterone circadian rhythm in staggerer (Rora sg/sg) mutant mice.}, author={Florence Fr{\'e}d{\'e}ric and Colette Chianale and Charles A. Oliver and Jean Mariani}, journal={Journal of neuroscience research}, year={2006}, volume={83 8}, pages={1525-32} }