Enhanced ectodysplasin‐A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form

@article{Mou2008EnhancedER,
  title={Enhanced ectodysplasin‐A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form},
  author={C. Mou and Helen A. Thomason and Pamela M. Willan and Christopher D. Clowes and W. E. Harris and Caroline F Drew and J. Dixon and M. Dixon and D. Headon},
  journal={Human Mutation},
  year={2008},
  volume={29}
}
  • C. Mou, Helen A. Thomason, +6 authors D. Headon
  • Published 2008
  • Biology, Medicine
  • Human Mutation
  • Hair morphology differs dramatically between human populations: people of East Asian ancestry typically have a coarse hair texture, with individual fibers being straight, of large diameter, and cylindrical when compared to hair of European or African origin. Ectodysplasin‐A receptor (EDAR) is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family involved in the development of hair follicles, teeth, and sweat glands. Analyses of genome‐wide polymorphism data from multiple… CONTINUE READING
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