Enhanced early chondrogenesis in articular defects following arthroscopic mesenchymal stem cell implantation in an equine model.

@article{Wilke2007EnhancedEC,
  title={Enhanced early chondrogenesis in articular defects following arthroscopic mesenchymal stem cell implantation in an equine model.},
  author={Markus M Wilke and Daryl V. Nydam and Alan J. Nixon},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2007},
  volume={25 7},
  pages={913-25}
}
Mesenchymal stem cells (MSCs) provide an important source of pluripotent cells for musculoskeletal tissue repair. This study examined the impact of MSC implantation on cartilage healing characteristics in a large animal model. Twelve full-thickness 15-mm cartilage lesions in the femoropatellar articulations of six young mature horses were repaired by injection of a self-polymerizing autogenous fibrin vehicle containing mesenchymal stem cells, or autogenous fibrin alone in control joints… CONTINUE READING
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