Enhanced differentiation of human embryonic stem cells on extracellular matrix-containing osteomimetic scaffolds for bone tissue engineering.

@article{Rutledge2014EnhancedDO,
  title={Enhanced differentiation of human embryonic stem cells on extracellular matrix-containing osteomimetic scaffolds for bone tissue engineering.},
  author={Katy E Rutledge and Qingsu Cheng and Marina V Pryzhkova and Greg M. Harris and Ehsan Jabbarzadeh},
  journal={Tissue engineering. Part C, Methods},
  year={2014},
  volume={20 11},
  pages={865-74}
}
Current methods of treating critical size bone defects include autografts and allografts, however, both present major limitations including donor-site morbidity, risk of disease transmission, and immune rejection. Tissue engineering provides a promising alternative to circumvent these shortcomings through the use of autologous cells, three-dimensional scaffolds, and growth factors. We investigated the development of a scaffold with native bone extracellular matrix (ECM) components for directing… CONTINUE READING
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Efficient FUNCTIONAL TISSUE ENGINEERING FOR BONE REPAIR 873 differentiation of human embryonic stem cells into a homogeneous population of osteoprogenitor-like cells

I. Mateizel, A. De Becker, +3 authors R Cornelissen
Reprod Biomed Online 16, • 2008

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