Enhanced detection of reversible perfusion defects by Tc-99m sestamibi compared to Tc-99m tetrofosmin during vasodilator stress SPECT imaging in mild-to-moderate coronary artery disease.

@article{Soman2001EnhancedDO,
  title={Enhanced detection of reversible perfusion defects by Tc-99m sestamibi compared to Tc-99m tetrofosmin during vasodilator stress SPECT imaging in mild-to-moderate coronary artery disease.},
  author={Prem Soman and Raymond Taillefer and E. Gordon Depuey and James E. Udelson and Avijit Lahiri},
  journal={Journal of the American College of Cardiology},
  year={2001},
  volume={37 2},
  pages={458-62}
}
OBJECTIVES We prospectively compared dipyridamole single-photon emission computed tomography (SPECT) imaging with Tc-99m sestamibi and Tc-99m tetrofosmin for the detection of reversible perfusion defects in patients with mild-to-moderate coronary artery disease. BACKGROUND Tc-99m tetrofosmin has a lower first-pass myocardial extraction fraction compared to Tc-99m sestamibi and thus could underestimate mild perfusion defects. METHODS Eighty-one patients with 50% to 90% stenosis in one or two… CONTINUE READING