Enhanced detection in brain activation maps using a multifiltering approach.

@article{Poline1994EnhancedDI,
  title={Enhanced detection in brain activation maps using a multifiltering approach.},
  author={Jean-Baptiste Poline and Bernard Mazoyer},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={1994},
  volume={14 4},
  pages={639-42}
}
Current methods for detecting activation foci in positron emission tomography difference images include a low pass filtering step aimed at improving the signal-to-noise ratio. However, we show that detection sensitivity depends both on the activation signal and the filter sizes. Therefore, we propose to improve current detection methods by using a multifiltering strategy that is shown to be more sensitive when various kinds of signals are present in the brain activation images. 

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