Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line.

Abstract

BACKGROUND The outcome of triple negative breast cancer is still poor and requires improvement with better therapy options. Autophagy has recently been shown to play a role in anticancer drug resistance. Therefore, we investigated if the effectiveness of doxorubicin was augmented by the inhibition of autophagy. METHODS MDA-MB-231 was used as a model cell… (More)
DOI: 10.1016/j.bbagen.2016.11.013

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Cite this paper

@article{Aydinlik2017EnhancedCA, title={Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line.}, author={Seyma Aydinlik and Merve Erkisa and Buse Cevatemre and Mehmet Sarimahmut and Egemen Dere and Ferda Ari and Engin Engin Ulukaya}, journal={Biochimica et biophysica acta}, year={2017}, volume={1861 2}, pages={49-57} }