Enhanced cortisol response to stress in children in autism.

  title={Enhanced cortisol response to stress in children in autism.},
  author={Eve G. Spratt and Joyce S. Nicholas and Kathleen T. Brady and Laura Arnstein Carpenter and Charles R. Hatcher and Kirk A Meekins and Richard W. Furlanetto and Jane M. Charles},
  journal={Journal of autism and developmental disorders},
  volume={42 1},
Children with Autism often show difficulties in adapting to change. Previous studies of cortisol, a neurobiologic stress hormone reflecting hypothalamic-pituitary-adrenal (HPA) axis activity, in children with autism have demonstrated variable results. This study measured cortisol levels in children with and without Autism: (1) at rest; (2) in a novel environment; and (3) in response to a blood draw stressor. A significantly higher serum cortisol response was found in the group of children with… CONTINUE READING