Enhanced chondrogenic differentiation of human mesenchymal stem cells in silk fibroin/chitosan/glycosaminoglycan scaffolds under dynamic culture condition.

@article{Agrawal2019EnhancedCD,
  title={Enhanced chondrogenic differentiation of human mesenchymal stem cells in silk fibroin/chitosan/glycosaminoglycan scaffolds under dynamic culture condition.},
  author={Parinita Agrawal and Krishna Pramanik},
  journal={Differentiation; research in biological diversity},
  year={2019},
  volume={110},
  pages={
          36-48
        }
}
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14 Citations
Background Citations
3
Results Citations
1

14 Citations

Synergetic integrations of bone marrow stem cells and transforming growth factor‐β1 loaded chitosan nanoparticles blended silk fibroin injectable hydrogel to enhance repair and regeneration potential in articular cartilage tissue
TLDR
Overall, it is concluded that the TGF‐β1‐SF/PCS injectable hydrogel demonstrates enhanced in vitro and in vivo tissue regeneration properties, which lead to efficacious therapeutic potential in cartilage regeneration.
Cartilage Repair Using Clematis Triterpenoid Saponin Delivery Microcarrier, Cultured in a Microgravity Bioreactor Prior to Application in Rabbit Model.
TLDR
Results provide an alternative preparation method for drug-delivered SF microcarrier and a culture method for maintaining the chondrogenic phenotype of seed cells based on the microgravity environment.
Dynamic process enhancement on chitosan/gelatin/nano-hydroxyapatite-bone derived multilayer scaffold for osteochondral tissue repair.
Bioactive Silk Fibroin-Based Hybrid Biomaterials for Musculoskeletal Engineering: Recent Progress and Perspectives.
TLDR
The physical and biological performances both in vitro and in vivo study of several common silk-based hybrid biomaterials in musculoskeletal engineering will provide a research perspective to promote the further improvement and development of silk-fibroin hybrid biommaterials for improved musculo- skeletal engineering.
Human mesenchymal stem cell therapy for cartilage repair: Review on isolation, expansion, and constructs.
Click Functionalized, Tissue-Specific Hydrogels for Osteochondral Tissue Engineering.
TLDR
The findings establish the versatility of this click functionalized hydrogel system as well as its ability to promote in vitro development of osteochondral tissue phenotypes.
Cytokine Directed Chondroblast Trans-Differentiation: JAK Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts
TLDR
Results showed the absence of intermediate induced pluripotent stem cell formation and the resulting aggregates showed clear hyaline and hypertrophic cartilage and tumor formation was absent in sub-cutaneous capsules transplanted in SCID mice.
Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration
TLDR
It is demonstrated that the supplementation of laminins to DPEM contributes to the odontogenic differentiation of cells and to the formation of odontoblast layer in dental pulp regeneration.
Tissue engineering of different cartilage types: a review of different approaches and recent advances
Cartilage is a connective tissue that serves as a structural support for maintaining the shape for specific appendices (nose, ear) and also helps for shock absorption when present in joints.…
Tissue Engineering Approaches and Generation of Insulin-Producing Cells to Treat Type 1 Diabetes.
TLDR
In vitro and in vivo evidence suggests that scaffold-based TE can improves the viability and function of IPCs, and a framework for prospective research based on data is offered.
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