Enhanced central and conduit pulmonary arterial reservoir function offsets reduced ductal systolic outflow during constriction of the fetal ductus arteriosus.

@article{Smolich2012EnhancedCA,
  title={Enhanced central and conduit pulmonary arterial reservoir function offsets reduced ductal systolic outflow during constriction of the fetal ductus arteriosus.},
  author={Joseph J. Smolich and Daniel J. Penny and Jonathan P. Mynard},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2012},
  volume={302 1},
  pages={R175-83}
}
Constriction of the fetal ductus arteriosus (DA) has disparate effects on mean and phasic hemodynamics, as mean DA blood flow is preserved until constriction is severe, but DA systolic and diastolic blood velocities change with only mild constriction. To determine the basis of this disparity and its physiological significance, seven anesthetized late… CONTINUE READING