Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells.

@article{Moriyama2010EnhancedCM,
  title={Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells.},
  author={Taiki Moriyama and Kenoki Ohuchida and Kazuhiro Mizumoto and Lin Cui and Naoki Ikenaga and Norihiro Sato and Masao Tanaka},
  journal={Cancer},
  year={2010},
  volume={116 14},
  pages={3357-68}
}
BACKGROUND Recently, cancer stem cells have been reported as a new therapeutic target in pancreatic cancer as well as other cancers, but the specific role of these cells is unknown. METHODS The authors investigated the functional roles of CD133+ cells, 1 of the putative cancer stem cell candidates in pancreatic cancer. CD133 expression was assessed in human pancreatic cancer and cancer cell lines by quantitative real-time reverse transcriptase polymerase chain reaction and flow cytometry… CONTINUE READING

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