Enhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia

  title={Enhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia},
  author={Rodrigo Iturriaga and David Crist{\'o}bal Andrade and Rodrigo Del Rio},
  booktitle={Front. Physiol.},
The carotid body (CB) plays a main role in the maintenance of the oxygen homeostasis. The hypoxic stimulation of the CB increases the chemosensory discharge, which in turn elicits reflex sympathetic, cardiovascular, and ventilatory adjustments. An exacerbate carotid chemosensory activity has been associated with human sympathetic-mediated diseases such as hypertension, insulin resistance, heart failure, and obstructive sleep apnea (OSA). Indeed, the CB chemosensory discharge becomes tonically… CONTINUE READING
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