Enhanced c-Fos in periaqueductal grey GABAergic neurons during opioid withdrawal.

@article{Chieng2005EnhancedCI,
  title={Enhanced c-Fos in periaqueductal grey GABAergic neurons during opioid withdrawal.},
  author={Billy C H Chieng and Catharina Hallberg and Fred J Nyberg and Macdonald J Christie},
  journal={Neuroreport},
  year={2005},
  volume={16 12},
  pages={1279-83}
}
The ventrolateral subdivision of periaqueductal grey is crucial for expression of opioid withdrawal signs. Previous investigations suggest that interneurons rather than the medullary projecting output neurons in this midbrain region are hyperexcited during opioid withdrawal. In the present study, transgenic mice with glutamic acid decarboxylase-containing… CONTINUE READING