Enhanced biofilm formation and reduced virulence of Actinobacillus pleuropneumoniae luxS mutant.

@article{Li2008EnhancedBF,
  title={Enhanced biofilm formation and reduced virulence of Actinobacillus pleuropneumoniae luxS mutant.},
  author={Lu Li and Rui Zhou and Tingting Li and Mingsong Kang and Yun Wan and Zhuofei Xu and Huanchun Chen},
  journal={Microbial pathogenesis},
  year={2008},
  volume={45 3},
  pages={192-200}
}
Actinobacillus pleuropneumoniae is the pathogen of porcine contagious pleuropneumonia causing great economic losses globally. LuxS is known to be involved in the interspecies quorum sensing by mediating the production of AI-2 signal molecule and play important roles in regulating various behaviors of bacteria. In this study, A. pleuropneumoniae was tested to be able to produce AI-2 like molecule. A luxS deletion mutant strain was constructed by homologous replacement, and its growth features… CONTINUE READING

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