Enhanced antiviral activity of soybean β-conglycinin-derived peptides by acylation with saturated fatty acids.

@article{Matemu2011EnhancedAA,
  title={Enhanced antiviral activity of soybean β-conglycinin-derived peptides by acylation with saturated fatty acids.},
  author={Athanasia Oswald Matemu and Kosuke Nakamura and Hisataka Kayahara and Hisashi Murasawa and Shigeru Katayama and Soichiro Nakamura},
  journal={Journal of food science},
  year={2011},
  volume={76 6},
  pages={M299-304}
}
Peptide mixtures prepared from soybean β-conglycinin (7S-peptides) were acylated with saturated fatty acids of different chain length (6C-18C) in order to improve their antiviral activity against Feline calicivirus (FCV) strain F9 which is a typical norovirus surrogate. Among the fatty acids varieties, it was revealed that 7S-peptides acylated with myristic and palmitic acids potently inhibited FCV replication. Myristorylation and palmitoylation of 7S-peptides kept host cells viability at 91.51… CONTINUE READING

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