Enhanced activation of eosinophils in peripheral blood and implications for eosinophilic esophagitis diagnosis.

@article{Botan2017EnhancedAO,
  title={Enhanced activation of eosinophils in peripheral blood and implications for eosinophilic esophagitis diagnosis.},
  author={Val{\'e}ria Botan and Tatiana Karla Dos Santos Borges and {\'E}rica Alessandra Rocha Alves and Shirley Claudino Pereira Couto and Heinrich Bender Kohnert Seidler and Maria Imaculada Muniz-Junqueira},
  journal={Journal of gastroenterology and hepatology},
  year={2017},
  volume={32 7},
  pages={1318-1327}
}
BACKGROUND AND AIM Eosinophils are markers of the eosinophilic esophagitis (EoE) disease, and this work aimed to assess whether activation of eosinophils could be a noninvasive test to contribute for EoE diagnosis. METHODS The activation state of peripheral blood eosinophils in EoE patients and control subjects was assessed based on the morphological aspects of the eosinophil after adherence to slide. Cyclooxygenase-2 and 5-lipoxygenase expressions were evaluated by means of… CONTINUE READING
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