Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion.

  title={Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion.},
  author={Ella S. M. Ng and David Jourd'heuil and J M Mccord and Daniel T Hernandez and Mitsukuni Yasui and Derrice Knight and Paul Kubes},
  journal={Circulation research},
  volume={94 4},
In the present study, we investigated whether inhaled nitric oxide (NO) was transported by plasma proteins, such as S-nitroso-albumin (SNO-Alb), in the feline circulation and whether this molecule delivers NO to the periphery under conditions of stress, specifically ischemia/reperfusion (I/R). A flow probe was interposed between the femoral and superior mesenteric artery for blood flow measurements, and a branch of the superior mesenteric vein was cannulated for arterial-venous sampling. In… CONTINUE READING


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