Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation.

Abstract

RNA polymerase (pol) III transcription, responsible for the synthesis of various stable RNAs, including 5 S rRNAs and tRNAs, is regulated by oncogenic proteins and tumor suppressors. Although it is well established that RNA pol III-dependent transcription is deregulated in transformed cells and malignant tumors, it has not been determined whether this… (More)
DOI: 10.1074/jbc.M802872200

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Cite this paper

@article{Johnson2008EnhancedRP, title={Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation.}, author={Sandra A. S. Johnson and Louis Dubeau and Deborah L. Johnson}, journal={The Journal of biological chemistry}, year={2008}, volume={283 28}, pages={19184-91} }