Enhanced Precision of Nanoparticle Phototargeting in Vivo at a Safe Irradiance.

Abstract

A large proportion of the payload delivered by nanoparticulate therapies is deposited not in the desired target destination but in off-target locations such as the liver and spleen. Here, we demonstrate that phototargeting can improve the specific targeting of nanoparticles to tumors. The combination of efficient triplet-triplet annihilation upconversion… (More)
DOI: 10.1021/acs.nanolett.6b01730

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